A multi-centre, prospective cohort study of whole blood gene expression in the tuberculosis-diabetes interaction Queiroz ATL, Vinhaes CL, Fukutani ER, Gupte AN, Kumar NP, Fukutani KF, Arriaga MB, Sterling TR, Babu S, Gaikwad S, Karyakarte R, Mave V, Paradkar M, Viswanathan V, Gupta A, Andrade BB, Kornfeld H; RePORT Brazil; RePORT India Consortia. Sci Rep. 2023 May 12;13(1):7769. doi: 10.1038/s41598-023-34847-9. PMID: 37173394; PMCID: PMC10180618.
The sound of silent RNA in tuberculosis and the lncRNA role on infection Rocha EF, Vinhaes CL, Araújo-Pereira M, Mota TF, Gupte AN, Kumar NP, Arriaga MB, Sterling TR, Babu S, Gaikwad S, Karyakarte R, Mave V, Kulkarni V, Paradkar M, Viswanathan V, Kornfeld H, Gupta A, Andrade BB, Queiroz ATL; RePORT Brazil; RePORT India Consortia. iScience. 2023 Dec 8;27(1):108662. doi: 10.1016/j.isci.2023.108662. PMID: 38205253; PMCID: PMC10777062.
RePORT India Multi-site Collaborations
Impact of undernutrition on tuberculosis treatment outcomes in India: A multicenter, prospective, cohort analysis Sinha P, Ponnuraja C, Gupte N, Prakash Babu S, Cox SR, Sarkar S, Mave V, Paradkar M, Cintron C, Govindarajan S, Kinikar A, Priya N, Gaikwad S, Thangakunam B, Devarajan A, Dhanasekaran M, Tornheim JA, Gupta A, Salgame P, Christopher DJ, Kornfeld H, Viswanathan V, Ellner JJ, Horsburgh CR, Gupte AN, Padmapriyadarsini C, Hochberg NS. Clin Infect Dis. 2023 Apr 17;76(8):1483-1491. doi: 10.1093/cid/ciac915. PMID: 36424864; PMCID: PMC10319769.
Impact of baseline nutritional status on tuberculosis severity in India: A multicenter prospective cohort analysis Du X, Ponnuraja C, Gupte N, Sarkar S, Gupta A, Christopher DJ, Kornfeld H, Viswanathan V, Ellner J, Horsburgh CR Jr, Padmapriyadarsini C, Sinha P. 1953. Open Forum Infect Dis. 2023 Nov 27;10(Suppl 2):ofad500.107. doi: 10.1093/ofid/ofad500.107. PMCID: PMC10677348.
Tuberculin test using Indian indigenous purified-protein derivative (PPD) shows only moderate agreement with international standard PPD Christopher DJ, Priya N, Shankar D, Isaac B, DeLuca A, Sarkar S, Prakash Babu S, Samuel P, Cattamanchi A, Gupta A, Ellner J, Srinivasan S, Cox S, Thangakunam B. J Clin Tuberc Other Mycobact Dis. 2023 Dec 1;34:100404. doi: 10.1016/j.jctube.2023.100404. PMID: 38174327; PMCID: PMC10761766.
Byramjee Jeejeebhoy Government Medical College National Institute for Research in Tuberculosis Johns Hopkins University (CRUs 106 & 105)
Characterising cause of death among people treated for drug-susceptible TB in India Cox SR, Padmapriyadarsini C, Mave V, Seth B, Thiruvengadam K, Gaikwad S, Sahasrabudhe TR, Sane M, Tornheim JA, Shrinivasa BM, Lokhande R, Barthwal MS, Shivakumar SVBY, Krishnan S, Santhappan R, Kinikar A, Kakrani AL, Paradkar M, Bollinger RC, Sekar K, Gupte AN, Hanna LE, Gupta A, Golub JE. Int J Tuberc Lung Dis. 2023 Jan 1;27(1):78-80. doi: 10.5588/ijtld.22.0454. PMID: 36853129.
Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis Hamada Y, Gupta RK, Quartagno M, Izzard A, Acuna-Villaorduna C, Altet N, Diel R, Dominguez J, Floyd S, Gupta A, Huerga H, Jones-López EC, Kinikar A, Lange C, van Leth F, Liu Q, Lu W, Lu P, Rueda IL, Martinez L, Mbandi SK, Muñoz L, Padilla ES, Paradkar M, Scriba T, Sester M, Shanaube K, Sharma SK, Sloot R, Sotgiu G, Thiruvengadam K, Vashishtha R, Abubakar I, Rangaka MX. EClinicalMedicine. 2023 Jan 5;56:101815. doi: 10.1016/j.eclinm.2022.101815. PMID: 36636295; PMCID: PMC9829704.
Sex differences in TB clinical presentation, drug exposure, and treatment outcomes in India Deshmukh S, Sane M, Gaikwad S, Sahasrabudhe T, Barthwal M, Lokhande R, Raskar S, Kagal A, Dharmshale S, Pradhan N, Gupte A, Alfarisi O, Gupta A, Dooley KE, Gupte N, Golub JE, Mave V. Chest. 2023 Apr;163(4):778-789. doi: 10.1016/j.chest.2022.09.024. Epub 2022 Sep 26. PMID: 36174745; PMCID: PMC10258435.
QuantiFERON supernatant-based host biomarkers predicting progression to active tuberculosis disease among household contacts of tuberculosis patients Daniel EA, Thiruvengadam K, Rajamanickam A, Chandrasekaran P, Pattabiraman S, Bhanu B, Sivaprakasam A, Paradkar M, Kulkarni V, Karyakarte R, Shivakumar SVBY, Mave V, Gupta A, Babu S, Hanna LE. Clin Infect Dis. 2023 May 24;76(10):1802-1813. doi: 10.1093/cid/ciac979. PMID: 36582115.
Comparative immune responses to Mycobacterium tuberculosis in people with latent infection or sterilizing protection Jalbert E, Liu C, Mave V, Lang N, Kagal A, Valvi C, Paradkar M, Gupte N, Lokhande R, Bharadwaj R, Kulkarni V, Gupta A, Weinberg A. iScience. 2023 Jul 20;26(8):107425. doi: 10.1016/j.isci.2023.107425. PMID: 37564701; PMCID: PMC10410524.
Early microbiologic markers of pulmonary tuberculosis treatment outcomes Paradkar MS, Pradhan NN, Balaji S, Gaikwad SN, Chavan A, Dharmashale SN, Sahasrabudhe T, Lokhande R, Deshmukh SA, Barthwal M, Atre S, Raskar SS, Sawant TU, Gupte AN, Kakrani A, Golub J, Padmapriyadarsini C, Gupta A, Gupte NA, Mave V. Ann Am Thorac Soc. 2023 Dec;20(12):1760-1768. doi: 10.1513/AnnalsATS.202302-144OC. PMID: 38038600; PMCID: PMC10704230.
Christian Medical College, Vellore University of Cambridge–University of Washington (CRU 101)
Pharmacokinetics of rifampicin, isoniazid & pyrazinamide during daily & intermittent dosing: A preliminary study Ramachandran G, Hemanth Kumar AK, Kannan T, Thangakunam B, Shankar D, Christopher DJ. Indian J Med Res. 2023 Feb-Mar;157(2&3):211-215. doi: 10.4103/ijmr.IJMR_1835_19. PMID: 36861539; PMCID: PMC10319390.
Continuous cough monitoring: a novel digital biomarker for TB diagnosis and treatment response monitoring Huddart S, Asege L, Jaganath D, Golla M, Dang H, Lovelina L, Derendinger B, Andama A, Christopher DJ, Nhung NV, Theron G, Denkinger CM, Nahid P, Cattamanchi A, Yu C. Int J Tuberc Lung Dis. 2023 Mar 1;27(3):221-222. doi: 10.5588/ijtld.22.0511. PMID: 36855045; PMCID: PMC9983626.
Placing the values and preferences of people most affected by TB at the center of screening and testing: an approach for reaching the unreached Kerkhoff AD, West NS, del Mar Castro M, Branigan D, Christopher DJ, Denkinger CM, Nhung NV, Theron G, Worodria W, Yu C, Muyoyeta M, Cattamanchi A. BMC Global Public Health. 2023 Nov 21;1(27). https://doi.org/10.1186/s44263-023-00027-0
Jawaharlal Institute of Postgraduate Medical Education & Research Boston Medical Center/Boston University Rutgers (CRU 102)
M. tuberculosis infection before, during and after pregnancy Knudsen S, Babu SP, Ramakrishnan J, Jenkins HE, Joseph N, Cintron C, Narasimhan PB, Salgame P, Hochberg NS, Hom DL, Ellner J, Horsburgh CR, Sarkar S. Int J Tuberc Lung Dis. 2023 Jan 1;27(1):72-74. doi: 10.5588/ijtld.22.0390. PMID: 36853122.
Not business as usual: Engaging the corporate sector in India’s TB elimination efforts Carwile M, Cintron C, Jain K, Buonomo G, Oliver M, Dauphinais M, Narasimhan PB, Prakash Babu S, Sarkar S, Locks L, Kulatilaka N, Hochberg N, Lakshminarayanan S, Sinha P. Glob Public Health. 2023 Jan;18(1):2120405. doi: 10.1080/17441692.2023.2216321. PMID: 37252903.
Effect of treatment adherence on the association between sex and unfavourable treatment outcomes among tuberculosis patients in Puducherry, India: a mediation analysis Barathi A, Krishnamoorthy Y, Sinha P, Horsburgh C, Hochberg N, Johnson E, Salgame P, Govindarajan S, Senbagavalli PB, Lakshinarayanan S, Roy G, Ellner J, Sarkar S. J Public Health (Oxf). 2023 Jun 14;45(2):304-311. doi: 10.1093/pubmed/fdac062. PMID: 35692180; PMCID: PMC10273348.
Development of prognostic scoring system for predicting 1-year mortality among pulmonary tuberculosis patients in South India Krishnamoorthy Y, Ezhumalai K, Murali S, Rajaa S, Majella MG, Sarkar S, Lakshminarayanan S, Joseph NM, Soundappan G, Prakash Babu S, Horsburgh C, Hochberg N, Johnson WE, Knudsen S, Pentakota SR, Salgame P, Roy G, Ellner J. J Public Health (Oxf). 2023 Jun 14;45(2):e184-e195. doi: 0.1093/pubmed/fdac087. PMID: 36038507; PMCID: PMC10273380.
Predictors of weight loss during the intensive phase of tuberculosis treatment in patients with drug-susceptible pulmonary tuberculosis in South India Kalva J, Babu SP, Narasimhan PB, Raghupathy K, Ezhumalai K, Knudsen S, Horsburgh CR, Hochberg N, Salgame P, Roy G, Ellner J, Sarkar S. J Public Health (Oxf). 2023 Aug 28;45(3):545-552. doi: 10.1093/pubmed/fdac141. PMID: 36451280; PMCID: PMC10470329.
MVDRC, NIRT-ICER, UMass
Chitinase and indoleamine 2, 3-dioxygenase are prognostic biomarkers for unfavorable treatment outcomes in pulmonary tuberculosis Kumar NP, Nancy A, Viswanathan V, Sivakumar S, Thiruvengadam K, Ahamed SF, Hissar S, Kornfeld H, Babu S. Front Immunol. 2023 Feb 6;14:1093640. doi: 10.3389/fimmu.2023.1093640. PMID: 36814914; PMCID: PMC9939892.
Longitudinal trends in glycated hemoglobin during and after tuberculosis treatment Kornfeld H, Procter-Gray E, Kumpatla S, Kane K, Li W, Magee MJ, Babu S, Viswanathan V. Diabetes Res Clin Pract. 2023 Feb;196:110242. doi: 10.1016/j.diabres.2023.110242. Epub 2023 Jan 7. PMID: 36627027.
Effect of prediabetes on tuberculosis treatment outcomes: A study from South India Viswanathan V, Devarajan A, Kumpatla S, Dhanasekaran M, Babu S, Kornfeld H. Diabetes Metab Syndr. 2023 Jul;17(7):102801. doi: 10.1016/j.dsx.2023.102801. Epub 2023 Jun 8. PMID: 37354752; PMCID: PMC10528008.
P.D. Hinduja National Hospital & Medical Research Center Johns Hopkins University (CRU 108)
Pharmacokinetic analysis of linezolid for multidrug resistant tuberculosis at a tertiary care centre in Mumbai, India Resendiz-Galvan JE, Arora PR, Abdelwahab MT, Udwadia ZF, Rodrigues C, Gupta A, Denti P, Ashavaid TF, Tornheim JA. Front Pharmacol. 2023 Jan 4;13:1081123. doi: 10.3389/fphar.2022.1081123. PMID: 36686664; PMCID: PMC9846493.
Swimming against the STREAM: Why STREAM 2 data cannot be easily applied to MDRTB patients across India Udwadia ZF, Patel JM, Batyala M, Tornheim JA, Rodrigues C. Lung India. 2023 May-Jun;40(3):290-291. doi: 10.4103/lungindia.lungindia_74_23. PMID: 37148033; PMCID: PMC10298808.
Targeted next-generation sequencing directly from sputum for comprehensive genetic information on drug-resistant Mycobacterium tuberculosis. Kambli P, Ajbani K, Kazi M, Sadani M, Naik S, Shetty A, Tornheim JA, Singh H, Rodrigues C. Tuberculosis (Edinb). 2021 Mar;127:102051. doi: 10.1016/j.tube.2021.102051. Epub 2021 Jan 8. PMID: 33450448.
Cycloserine did not increase depression incidence or severity at standard dosing for multidrug-resistant tuberculosis Tornheim JA, Udwadia ZF, Arora PR, Gajjar I, Gupte N, Sharma S, Karane M, Sawant N, Kharat N, Blum AJ, Shivakumar SV. Eur Respir J. 2022 Mar 24;59(3):2102511. doi: 10.1183/13993003.02511-2021. PMID: 34949698; PMCID: PMC8943271.
MVDRC
Acute Phase Proteins Are Baseline Predictors of Tuberculosis Treatment Failure Kumar NP, Moideen K, Nancy A, Viswanathan V, Thiruvengadam K, Sivakumar S, Hissar S, Kornfeld H, Babu S.. Front Immunol. 2021 Nov 15;12:731878. doi: 10.3389/fimmu.2021.731878. PMID: 34867953; PMCID: PMC8634481
Effect of anti-tuberculosis treatment on the systemic levels of tissue inhibitors of metalloproteinases in tuberculosis – Diabetes co-morbidity Kumar NP, Moideen K, Viswanathan V, Sivakumar S, Hissar S, Kornfeld H, Babu S.. J Clin Tuberc Other Mycobact Dis. 2021 Apr 22;23:100237. doi: 10.1016/j.jctube.2021.100237. PMID: 33997311; PMCID: PMC8100611.
Heightened microbial translocation is a prognostic biomarker of recurrent tuberculosis Kumar NP, Moideen K, Viswanathan V, Sivakumar S, Ahamed SF, Ponnuraja C, Hissar S, Kornfeld H, Babu S. Clin Infect Dis. 2022 Nov 14;75(10):1820-1826. doi: 10.1093/cid/ciac236. PMID: 35352112; PMCID: PMC9662171.
CMC VELLORE
MTB/RIF Ultra over Xpert® MTB/RIF in the diagnosis of extrapulmonary TB D. J. Christopher, V. Coelho, G. S. Ebby, D. Shankar, R. Gupta, B. Thangakunam, Departments of Pulmonary Medicine, General Surgery – Unit IV, Gastroenterology, and Respiratory Medicine, Christian Medical College, Vellore, India INT J TUBERC LUNG DIS 25(11):939–944 Q 2021. The Union. Nov 2021. DOI: http://dx.doi.org/10.5588/ijtld.21.0280
Deep LF-Net: Semantic lung segmentation from Indian chest radiographs including severely unhealthy images Anushikha Singh a, Brejesh Lall b, B.K. Panigrahi b, Anjali Agrawal c, Anurag Agrawal d, Balamugesh Thangakunam , D.J. Christopher, Biomedical Signal Processing and Control, Apr 2021 DOI: https://doi.org/10.1016/j.bspc.2021.102666
Accuracy of Xpert MTB/RIF Ultra for the diagnosis of tuberculosis in adult patients: a retrospective cohort study Kaswala C, Schmiedel Y, Kundu D, George MM, Dayanand D, Devasagayam E, S AM, Kumar SS, Michael JS, Ninan MM, Chacko G, Zachariah A, Sathyendra S, Hansdak SG, Iyadurai R, Christopher DJ, Gupta R, Karthik R, Abraham OC, Varghese GM. Int J Infect Dis. 2022 Sep;122:566-568. doi: 10.1016/j.ijid.2022.07.016. Epub 2022 Jul 8. PMID: 35811084.
Semantic segmentation of bone structures in chest X-rays including unhealthy radiographs: A robust and accurate approach Singh A, Lall B, Panigrahi BK, Agrawal A, Agrawal A, Thangakunam B, Christopher DJ. Int J Med Inform. 2022 Sep;165:104831. doi: 10.1016/j.ijmedinf.2022.104831. Epub 2022 Jul 18. PMID: 35870303.
Impact of undernutrition on tuberculosis treatment outcomes in India: A multicenter prospective cohort analysis Sinha P, Ponnuraja C, Gupte N, Babu SP, Cox SR, Sarkar S, Mave V, Paradkar M, Cintron C, Govindarajan S, Kinikar A, Priya N, Gaikwad S, Thangakunam B, Devarajan A, Dhanasekaran M, Tornheim JA, Gupta A, Salgame P, Christopher DJ, Kornfeld H, Viswanathan V, Ellner JJ, Horsburgh CR, Gupte AN, Padmapriyadarsini C, Hochberg NS. Clin Infect Dis. 2022 Nov 25:ciac915. doi: 10.1093/cid/ciac915. Epub ahead of print. PMID: 36424864.
JIPMER/RUTGERS
Accuracy of Timika X-ray scoring system to predict the treatment outcomes among tuberculosis patients in India. Yuvaraj Krishnamoorthy, Selby Knudsen, Sathish Rajaa, Subitha Lakshminarayanan, P.B. Senbagavalli, Jerrold Ellner, Charles Horsburgh, Natasha Hochberg, Padmini Salgame, Sonali Sarkar. IJTB (in press) Received 18 September 2020, Accepted 4 August 2021, Available online 11 August 2021. https://doi.org/10.1016/j.ijtb.2021.08.004.
Tuberculosis-Learning the Impact of Nutrition (TB LION): protocol for an interventional study to decrease TB risk in household contacts. Cintron C, Narasimhan PB, Locks L, Babu S, Sinha P, Rajkumari N, Kaipilyawar V, Bhargava A, Maloomian K, Chandrasekaran P, Verma S, Joseph N, Johnson WE, Wanke C, Horsburgh CR Jr, Ellner JJ, Sarkar S, Salgame P, Lakshminarayanan S, Hochberg NS. BMC Infect Dis. 2021 Oct 12;21(1):1058. doi: 10.1186/s12879-021-06734-z.
Comparison of profile and treatment outcomes between elderly and non-elderly tuberculosis patients in Puducherry and Tamil Nadu, South India. Murali S, Krishnamoorthy Y, Knudsen S, Roy G, Ellner J, Horsburgh CR, Hochberg N, Salgame P, Prakash Babu S, Sarkar S. PLoS One. 2021 Aug 27;16(8): e0256773.
Prevalence and factors associated with diabetes mellitus among tuberculosis patients in South India—a cross-sectional analytical study. Sathish Rajaa, Yuvaraj Krishnamoorthy, Selby Knudsen, Gautam Roy, Jerrold Ellner, Charles Horsburgh, Natasha Hochberg, Padmini Salgame, Govindarajan S, Senbagavalli Prakash Babu, Sonali Sarkar. BMJ Open 2021;11:e050542. doi: 10.1136/bmjopen-2021-050542
‘People listen more to what actors say’: A qualitative study of tuberculosis-related knowledge, behaviours, stigma, and potential interventions in Puducherry, India. Sabin LL, Thulasingam M, Carwile M, Babu SP, Knudsen S, Dong L, Stephens J, Fernandes P, Cintron C, Horsburgh CR, Salgame P, Ellner JJ, Sarkar S, Hochberg NS. Glob Public Health. 2021 Oct 16:1-13.
Prevalence and Risk Factors associated with Latent Tuberculosis Infection among Household Contacts of Smear Positive Pulmonary Tuberculosis patients in South India. Krishnamoorthy Y, Ezhumalai K, Murali S, Rajaa S, Jose M, Sathishkumar A, Govindarajan S, Horsburgh C, Hochberg N, Johnson E, Knudsen S. Tropical Medicine & International Health. 2021 Oct 15. https://doi.org/10.1111/tmi.13693
Reasons for refusal among patients with tuberculosis and their household contacts to participate in an observational cohort study. Raghupathy Kalaivani, Knudsen Selby, Ellner Jerrold, Horsburg Charles, Hochberg Natasha, Salgame Padmini, Chinnakali Palanivel, Prakashbabu Senbagavalli, Sarkar Sonali. Perspect Clin Res. 2021 Oct-Dec;12(4):234-235. doi: 10.4103/picr. Epub 2021 Sep 20. PMID: 34760653; PMCID: PMC8525795.
Severe undernutrition in children affects tuberculin skin test performance in Southern India. Reddy D, Ma Y, Lakshminarayanan S, Sahu S, White LF, Reshma A, Roy G, Salgame P, Knudsen S, Cintron C, Ellner JJ, Horsburgh CR Jr, Sarkar S, Hochberg NS. Severe undernutrition in children affects tuberculin skin test performance in Southern India. PLoS One. 2021 Jul 16;16(7):e0250304. doi: 10.1371/journal.pone.0250304. PMID: 34270546; PMCID: PMC8284816.
Comparing Tuberculosis Gene Signatures in Malnourished Individuals using the TBSignatureProfiler Johnson WE, Odom A, Cintron C, Muthaiah M, Knudsen S, Joseph N, Jenkins DF, , Babu S, Lakshminarayanan S, Zhao Y, Nankya E, Horsburgh CR Jr, Roy G, Ellner JJ, Sarkar S, Salgame P*, Hochberg NS. BMC Inf Dis 2021; 21(1):106. PMID: 33482742.
Health-related quality of life and its effect on TB treatment outcomes. Roy N, Krishnamoorthy Y, Rajaa S, Ezhumalai K, Madhusudhanan S, Raghupathy K, Knudsen S, Horsburgh CR, Hochberg NS, Salgame P, Ellner J, Subitha L, Babu SP, Sarkar S. The International Journal of Tuberculosis and Lung Disease, Volume 25 (4) 1 April 2021, pp. 318-320(3) PMID: 33762076. DOI: 10.5588/ijtld.20.0722
Comparison of IGRA and TST in the diagnosis of latent tuberculosis among women of reproductive age in South India Senbagavalli Prakash Babu, Komala Ezhumalai, Kalaivani Raghupathy, Madhusudanan Sundaresan, Komal Jain, Prakash Babu Narasimhan, Selby Knudsen, Robert Horsburgh, Natasha Hochberg, Padmini Salgame, Jerrold Ellner, Sonali Sarkar. Indian Journal of Tuberculosis https://doi.org/10.1016/j.ijtb.2022.03.011.
Effect of treatment adherence on the association between sex and unfavourable treatment outcomes among tuberculosis patients in Puducherry, India: a mediation analysis Barathi A, Krishnamoorthy Y, Sinha P, Horsburgh C, Hochberg N, Johnson E, Salgame P, Govindarajan S, Senbagavalli PB, Lakshinarayanan S, Roy G, Ellner J, Sarkar S. J Public Health (Oxf). 2022 Jun 11:fdac062. doi: 10.1093/pubmed/fdac062. Epub ahead of print. PMID: 35692180.
Development of prognostic scoring system for predicting 1-year mortality among pulmonary tuberculosis patients in South India Krishnamoorthy Y, Ezhumalai K, Murali S, Rajaa S, Majella MG, Sarkar S, Lakshminarayanan S, Joseph NM, Soundappan G, Prakash Babu S, Horsburgh C, Hochberg N, Johnson WE, Knudsen S, Pentakota SR, Salgame P, Roy G, Ellner J. J Public Health (Oxf). 2022 Aug 27:fdac087. doi: 10.1093/pubmed/fdac087. Epub ahead of print. PMID: 36038507.
Malnutrition leads to increased inflammation and expression of tuberculosis risk signatures in recently exposed household contacts of pulmonary tuberculosis VanValkenburg A, Kaipilyawar V, Sarkar S, Lakshminarayanan S, Cintron C, Prakash Babu S, Knudsen S, Joseph NM, Horsburgh CR, Sinha P, Ellner JJ, Narasimhan PB, Johnson WE, Hochberg NS, Salgame P. Front Immunol. 2022 Sep 28;13:1011166. doi: 10.3389/fimmu.2022.1011166. Erratum in: Front Immunol. 2022 Oct 20;13:1064883. PMID: 36248906; PMCID: PMC9554585.
Predictors of weight loss during the intensive phase of tuberculosis treatment in patients with drug-susceptible pulmonary tuberculosis in South India Kalva J, Babu SP, Narasimhan PB, Raghupathy K, Ezhumalai K, Knudsen S, Horsburgh CR, Hochberg N, Salgame P, Roy G, Ellner J, Sarkar S. J Public Health (Oxf). 2022 Nov 30:fdac141. doi: 10.1093/pubmed/fdac141. Epub ahead of print. PMID: 36451280.
Impact of Undernutrition on Tuberculosis Treatment Outcomes in India: A Multicenter Prospective Cohort Analysis. Sinha P, Ponnuraja C, Gupte N, Babu SP, Cox SR, Sarkar S, Mave V, Paradkar M, Cintron C, Govindarajan S, Kinikar A, Priya N, Gaikwad S, Thangakunam B, Devarajan A, Dhanasekaran M, Tornheim JA, Gupta A, Salgame P, Christopher DJ, Kornfeld H, Viswanathan V, Ellner JJ, Horsburgh CR, Gupte AN, Padmapriyadarsini C, Hochberg NS. Clin Infect Dis. 2022 Nov 25:ciac915. doi: 10.1093/cid/ciac915. Epub ahead of print. PMID: 36424864.
Development and validation of a parsimonious TB gene signature using the digital NanoString nCounter platform Kaipilyawar V, Zhao Y, Wang X, Joseph NM, Knudsen S, Babu SP, Muthaiah M, Hochberg NS, Sarkar S, Horsburgh CR, Jr., Ellner JJ, Johnson WE, Salgame P. Clin Infect Dis. 2022. Epub 2022/01/12. doi:10.1093/cid/ciac010. PubMed PMID: 35015839.
BMMRC
Defective expansion and function of memory like natural killer cells in HIV+ individuals with latent tuberculosis infection. Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Siva Sai Krovvidi, Ramakrishna Vankayalapati, Vijaya Lakshmi Valluri PLoS ONE 16(9): e0257185.
Reduced thyroxine production in young household contacts of tuberculosis patients increases active tuberculosis disease risk Devalraju KP, Tripathi D, Neela VSK, Paidipally P, Bogam AK, Mallidi V, Sykam A, Singh KP, Ansari MS, Vankayalapati R, Valluri VL. JCI Insight. 2021;6(13):e148271.
Metabolites enhance innate resistance to human Mycobacterium tuberculosis infection Tripathi D, Devalraju KP, Neela VSK, Paidipally P, Radhakrishnan RK, Mukherjee T, Dozmorov I, Bogam AK, Mallidi V, Ansari MS, Valluri VL, Vankayalapati R. JCI Insight. 2022 Nov 22;7(22):e152357. doi: 10.1172/jci.insight.152357. PMID: 36509283; PMCID: PMC9746823.
BJGMC/ CTRIUMPH
Unhealthy alcohol use is independently associated with unfavorable TB treatment outcomes among Indian men. Cox SR, Gupte AN, Thomas B, Gaikwad S, Mave V, Padmapriyadarsini C, Sahasrabudhe TR, Kadam D, Gupte N, Hanna LE, Kagal A, Paradkar M, Thiruvengadam K, Jain D, Atre S, Sekar K, Raskar S, Shivakumar SVBY, Santhappan R, Deshmukh S, Pradhan N, Kulkarni V, Kakrani A, Barthwal MS, Sawant T, DeLuca A, Suryavanshi N, Chander G, Bollinger R, Golub JE, Gupta A. doi: 10.5588/ijtld.20.0778. PMID: 33688806.
Host Lipidome Predicts Tuberculosis Treatment Failure Rupak Shivakoti, John W Newman, Luke Elizabeth Hanna, Artur T L Queiroz, Kamil Borkowski, Akshay N Gupte, Mandar Paradkar, Pattabiraman Satyamurthi, Vandana Kulkarni, Murugesh Selva, Neeta Pradhan, Shri Vijay Bala Yogendra Shivakumar, Saravanan Natarajan, Ramesh Karunaianatham, Nikhil Gupte, Kannan Thiruvengadam, Oliver Fiehn, Renu Bharadwaj, Anju Kagal, Sanjay Gaikwad, Shashikala Sangle, Jonathan E. Golub, Bruno B Andrade, Vidya Mave, Amita Gupta, Padmapriyadarshini Chandrasekaran. DOI: 10.1183/13993003.04532-2020
Baseline IL-6 is a biomarker for unfavorable tuberculosis treatment outcomes: a multi-site discovery and validation study Akshay N. Gupte, Pavan Kumar, Mariana Araújo-Pereira, Vandana Kulkarni, Mandar Paradkar, Neeta Pradhan, Padmapriya Darasini, Luke Hanna, Shri Vijay Bala Yogendra Shivakumar, Neesha Rockwood, Elsa Du Bruyn, Rajesh Karyakarte, Sanjay Gaikwad, Robert Bollinger, Jonathan Golub, Nikhil Gupte, Vijay Viswanathan, Robert J. Wilkinson, Vidya Mave, Subash Babu, Hardy Kornfeld, Bruno B. Andrade, Amita Gupta.
Concomitant Pulmonary Disease is Common among Indian Patients With Extrapulmonary Tuberculosis. Shri Vijay Bala Yogendra, Shivakumar, Chandrasekaran Padmapriyadarshini, Amol Chavan, Mandar Paradkar, BM Shrinivasa, Akshay Gupte, Kavitha Dhanasekaran, Beena Thomas, Nishi Suryavanshi, Chandra Kumar Dolla, Sriram Selvaraju, Aarti Kinikar, Sanjay Gaikwad, Rewa Kholi, Gomathi Narayan Sivaramakrishnan, Neeta Pradhan, Luke Elizabeth Hanna, Vandana Kulkarni, Andrea DeLuca, Samyra R. Cox, Lakshmi Murali, Kannan Thiruvengadam, Swapnil Raskar, Geeta Ramachandran, Jonathan E. Golub, Nikhil Gupte, Vidya Mave, Soumya Swaminathan MD, Amita Gupta, Robert C Bollinger for the CTRIUMPh-RePORT India Study Team.
Whole Genome Sequencing Assessing Impact of Diabetes Mellitus on Tuberculosis Mutations and Type of Recurrence in India Vidya Mave, Liang Chen, Umadevi Ranganathan, Dileep Kadam, Rahul Lokhande, Shivkumar, Anju Kagal, Neeta Pradhan, Vijay Vishwanathan, Amita Gupta, Padmapriyadarshini, Jonathan E. Golub, Nikhil Gupte, Barun Mathema, Barry Kreiswirth.
Modern lineages of Mycobacterium tuberculosis were recently introduced in western India and demonstrate increased transmissibility Avika Dixit, Anju Kagal, Yasha Ektefaie, Luca Freschi, Rahul Lokhande, Matthias Groeschel, Jeffrey A. Tornheim, Nikhil Gupte, Neeta Pradhan, Deelip Kadam, Marco Schito, David Engelthaler, Amita Gupta, Jonathan Golub, Vidya Mave, Maha Farhat.
Sex differences in tuberculosis clinical presentation, drug exposure, and treatment outcomes in Pune, India. Sona Deshmukh, Manasi Sane, Sanjay Gaikwad, Tushar Sahasrabudhe, Madhusudan Barthwal, Rahul Lokhande, Swapnil Raskar, Anju Kagal, Sujata Dharmshale, Neeta Pradhan, Akshay Gupte, Omamah Alfarisi, Amita Gupta, Kelly E. Dooley, Nikhil Gupte, Jonathan E. Golub, Vidya Mave.
QuantiFERON supernatant-based host biomarkers predicting progression to active tuberculosis disease among household contacts of tuberculosis patients Daniel EA, Thiruvengadam K, Rajamanickam A, Chandrasekaran P, Pattabiraman S, Bhanu B, Sivaprakasam A, Paradkar M, Kulkarni V, Karyakarte R, Shivakumar SVBY, Mave V, Gupta A, Babu S, Hanna LE. Clin Infect Dis. 2022 Dec 30:ciac979. doi: 10.1093/cid/ciac979. Epub ahead of print. PMID: 36582115.
The kynurenine/tryptophan ratio is a sensitive biomarker for the diagnosis of pediatric tuberculosis among Indian children Tornheim JA, Paradkar M, Zhao H, Kulkarni V, Pradhan N, Kinikar A, Kagal A, Gupte N, Mave V, Gupta A, Karakousis PC. Front Immunol. 2022 Jan 12;12:774043. doi: 10.3389/fimmu.2021.774043. PMID: 35095848; PMCID: PMC8790563.
Year 2021
Deep LF-Net: Semantic lung segmentation from Indian chest radiographs including severely unhealthy images Anushikha Singh, Brejesh Lall, BK Panigrahi, Anjali Agrawal, Anurag Agrawal, Balamugesh Thangakunam, DJ Christopher, Biomedical Signal Processing and Control, https://doi.org/10.1016/j.bspc.2021.102666.
Measuring tuberculosis drugs in hair in adults and children as a tool to monitor exposure and outcomes Mave V, Kadam D, Gaikwad S, Kinikar A, Aguilar D, Chavan A, Paradkar M, Shivakumar SVBY, Bharadwaj R, Kagal A, Suryavanshi N, Golub J, Kulkarni V, Dooley K, Gupta A, Bachetti P, Gerona R, Gupte N, Gandhi M. Int J Tuberc Lung Dis. 2021 Jan 1;25(1):52-60. doi: 10.5588/ijtld.20.0574. PMID: 33384045.
Potential drug-drug interactions between anti–tubercular and non-tubercular drugs among patients with pulmonary tuberculosis in Puducherry and Tamil Nadu Marie CJ, Senbagavalli PB, Ezhumalai K, Knudsen S, Horsburgh CR, Hochberg NS, Salgame P, Ellner J, Sarkar S. European Journal of Pharmaceutical and Medical Research. 2021;8(1), 427-440.
Comparing tuberculosis gene signatures in malnourished individuals using the TBSignatureProfiler Johnson WE, Odom A , Cintron C, Muthaiah M, Knudsen S , Joseph N, Prakash Babu S, Lakshminarayanan S, Jenkins DF, Zhao Y, Nankya E, Horsburgh CR, Roy G, Ellner J, Sarkar S, Salgame P, Hochberg NS. BMC Infect Dis. 2021 Jan 22;21(1):106. doi: 10.1186/s12879-020-05598-z. PMID: 33482742; PMCID: PMC7821401.
Food for thought: addressing undernutrition to end TB Sinha P, Lönnroth K, Bhargava A, Heysell SK, Sarkar S, Salgame P, Rudgard W, Boccia D, Van Aartsen D, Hochberg NS. Lancet Infectious Diseases. 2020 (Accepted, in press)
Physical health-related quality of life and its effect on treatment outcomes among pulmonary tuberculosis patients Roy N, Krishnamoorthy Y, Rajaa S, Ezhumalai K, Madhusudhanan S, Raghupathy K, Knudsen S, Horsburgh CR, Hochberg NS, Salgame P, Ellner J, Subitha L, Babu SP, Sarkar S. Health-related quality of life and its effect on TB treatment outcomes. Int J Tuberc Lung Dis. 2021 Apr 1;25(4):318-320.
Reasons for refusal among patients with tuberculosis and their household contacts to participate in an observational cohort study Raghupathy K , Knudsen S, Ellner J, Horsburgh RC, Hochberg N, Salgame P, Chinnakali P, Prakashbabu P, Sarkar S. (Accepted: Perspectives in Clinical Research, 2021)
Unhealthy alcohol use independently associated with unfavorable tuberculosis treatment outcomes among Indian men Cox SR, Gupte AN, Thomas B, Gaikwad S, Mave V, Padmapriyadarsini C, Sahasrabudhe RT, Kadam D, Gupte N, Hanna LE, Kagal A, Paradkar M, Thiruvengadam K, Jain D, Atre S, Sekar K, Raskar S, Shivakumar SVBY, Santhappan R, Deshmukh S, Pradhan N, Kulkarni V, Kakrani A, Barathwal MS, Sawant T, Deluca A, Suryavanshi N, Chander G, Bollinger R, Golub JE, Gupta A. (Accepted: IJTLD)
A two-gene signature for tuberculosis diagnosis in persons with advanced HIV Kulkarni V, Queiroz ATL, Sangle S, Kagal A, Salvi S, Gupta A, Ellner J, Kadam D, Rolla VC, Andrade BB, Salgame P, Mave V. (Accepted: Frontiers in Immunology)
Substantial early mortality among tuberculosis patients with diabetes mellitus, particularly among patients not receiving metformin, in India Mave V, Gaikwad S, Barthwal M, Chandanwale A, Lokhande R, Kadam D, Dharmshale S, Bharadwaj R, Kagal A, Pradhan N, Deshmukh S, Atre S, Sahasrabudhe T, Meshram S, Kakrani A, Kulkarni V, Raskar S, Suryavanshi N, Kornfeld H, Dooley KE, Chon S, Gupte A, Gupta A, Gupte N, Golub JE. (Accepted: OFID)
Year 2020
Integration of metabolomics and transcriptomics reveals novel biomarkers in the blood for tuberculosis diagnosis in children Dutta NK, Tornheim JA, Fukutani KF, Paradkar M, Tiburcio RT, Kinikar A, Valvi C, Kulkarni V, Pradhan N, Shivakumar SVBY, Kagal A, Gupte A, Gupte N, Mave V, Gupta A, Andrade BB, Karakousis PC for the CTRIUMPh RePORT India Study Team. Scientific Reports. 2020 Nov 11;10(19527). PMID: 33177551; PMCID: PMC7658223.
Assessment of persistent depressive symptoms among tuberculosis patients in India Suryavanshi N, Sane M, Gaikwad S, Paradkar M, Mave V, Padmapriyadarsini C, Shivakumar SVBY, Gupta A, Gupte N, Thomas B for CTRIUMPH RePORT India study. IJTLD. 2020 Nov 1;24(11):1208-1211(4). PMID: 33172530.
Higher IL-6 levels and changes in TGF-β are associated with lung impairment in pulmonary tuberculosis Gupte AN, Selvaraju S, Gaikwad S, Mave V, Kumar P, Babu S, Andrade BB, Checkley W, Bollinger R, Gupta A for the CTRIUMPH study team. ERJ Open Research. 2020 September. DOI: 10.1183/23120541.00390-2020.
Tuberculosis preventive treatment should be considered for all household contacts of pulmonary TB patients in India Paradkar M, Padmapriyadarsini C, Jain D, Shivakumar SVBY, Thiruvengadam K, Gupte AN, Thomas B, Kinikar A, Sekar K, Bharadwaj B, Dolla CK, Gaikwad S, Elilarasi S, Lokhande R, Reddy D, Murali L, Kulkarni V, Pradhan N, Elizabeth Hanna L, Pattabiraman S, Kohli1 R, Nayagam R, Suryavanshi1 N, Shrinivasa BM, Cox SR, Sriram Selvaraju S, Gupte N, Mave V, Gupta A, Bollinger RC, for the CTRIUMPH-RePORT India Study Team. PLOS One. 2020 July 29;15(7):e0236743. https://doi.org/10.1371/journal.pone.0236743. PMID: 32726367; PMCID: PMC7390377.
Xpert Ultra is better than Xpert, but using biopsy, samples may be even better Thangakunam B, Christopher DJ. Chest. 2020 Aug;158(2):829-830. doi: 10.1016/j.chest.2020.02.078. PMID: 32768069
Screening for prevalence of current TB disease and latent TB infection in type 2 diabetes mellitus patients attending a diabetic clinic in an Indian tertiary care hospital Dabhi PA, Thangakunam B, Prince J, Gupta R, Nihal T, Naik D, Christopher DJ. PLoS One. 2020 Jun 5;15(6):e0233385. doi: 10.1371/journal.pone.0233385. eCollection 2020. PMID: 32502176; PMCID: PMC7274437.
Burden of diabetes among patients with tuberculosis: 10-year experience from a tertiary care referral teaching hospital in South India Christopher DJ, Jeyaseelan L, Michael JS, Veeraraghavan B, Manipadam MT, David T, Gupta M, Yadav B. Lung India. May-Jun 2020;37(3):232-237. doi: 10.4103/lungindia.lungindia_111_19. PMID: 32367845; PMCID: PMC7353927.
Is routine pre-entry chest radiograph necessary in a high tuberculosis prevalence country? Jasper A, Gibikote S, Kirupakaran H, Christopher DJ, Mathews P. J Postgrad Med. Apr-Jun 2020;66(2):90-93. doi: 10.4103/jpgm.JPGM_462_19. PMID: 32270779; PMCID: PMC7239409.
How much do Indians pay for tuberculosis treatment? A cost analysis Sinha P, Carwile M, Bhargava A, Cintron C, Acuna-Villaorduna C, Lakshminarayanan S, Kulatilaka N, Locks L, Hochberg NS. Public Health Action. 2020 Sep 21;10(3):110-117. doi: 10.5588/pha.20.0017. PMID: 33134125; PMCID: PMC7577002.
Risk factors for death during treatment in pulmonary tuberculosis patients in South India: A cohort study Ramakrishnan J, Sarkar S, Chinnakali P, Lakshminarayanan S, Sahu S, Reshma A, et al. Indian Journal of Tuberculosis. 2020 Oct.
Neonatal tetanus in a nomadic population in South India: A clinicosocial case study Surendran G, Rehman T, Eliyas S, Kalaiselvy A, Sarkar S. Indian Journal of Community Medicine. 2020 Jul 1;45(3):384.
Oft-overlooked: controlling for undernutrition in epidemiological studies of tuberculosis Sinha P, Hochberg NS. Letter to the Editor. Lancet Infectious Diseases 2020; 20(5);540-541.
Household food insecurity among patients with pulmonary tuberculosis and its associated factors in South India: a cross-sectional analysis Ayiraveetil R, Sarkar S, Chinnakali P, Jeyashree K, Vijayageetha M, Thekkur P, Lakshminarayanan S, Knudsen S, Hochberg NS, Horsburgh CR, Ellner J, Roy G. BMJ Open. 2020 Feb 28;10(2):e033798; PMID: 32114470 ; PMCID: PMC7050349.
Predictors of loss to follow-up among male tuberculosis cases in Pondicherry and Tamil Nadu, India Zhou T, Lakshminarayanan S, Sarkar S, Knudsen S, Horsburgh CR Jr, Muthaiah M, Kan C, Salgame P, Ellner J, Roy G, Jenkins H, Hochberg NS. Am J Trop Med Hygiene; 2020. 103(3): 1050-56.
Evaluation of factors influencing Mycobacterium tuberculosis complex recovery and contamination rates in MGIT960 Ellappan K, Datta S, Muthuraj M, Lakshminarayanan S, Pleskunas JA, Horsburgh CR Jr, Salgame P, Hochberg N, Sarkar S, Ellner JJ, Roy G, Jose M, Vinod Kumar S, Joseph NM. Indian J Tuberculosis; 2020; published online 19 July. https://doi.org/10.1016/j.ijtb.2020.07.016.
Controlling for undernutrition in epidemiological studies of tuberculosis Sinha P, Hochberg NS. Lancet Infectious Diseases. 2020, 20(5): 540-541. PMID: 32359465.
MAL adaptor (TIRAP) S180L polymorphism and severity of disease among tuberculosis patients Saranathan R, Sathyamurthi P, Thiruvengadam K, Murugesan S, Shivakumar SVBY, NS Gomathi, Kavitha D, Paradkar M, Puvaneshwari R, Kannan M, Madheswaran A, Pradhan N, Kulkarni V, Gupte AN, Gupte N, Mave V, Bollinger RC, Gupta A, Padmapriyadarsini C, Hanna LE. Infection, Genetics, and Evolution. 2020 Jan(44). Epub ahead of print 2019 Oct 31. PMID: 31678649.
Association of plasma matrix metalloproteinase and tissue inhibitors of matrix metalloproteinase levels with adverse treatment outcomes among patients with pulmonary tuberculosis Kumar NP, Moideen K, Nancy A, Viswanathan V, Thiruvengadam K, Sivakumar S, Hissar S, Nair D, Banurekha VV, Kornfeld H, Babu S. JAMA Netw Open. 2020 Dec 1;3(12):e2027754. PMID: 33258908.
Plasma chemokines are baseline predictors of unfavorable treatment outcomes in pulmonary tuberculosis Kumar NP, Moideen K, Nancy A, Viswanathan V, Thiruvengadam K, Nair C, Banurekha VV, Sivakumar S, Hissar S, Kornfeld H, Babu S. Clin Infect Dis. 2020 Aug 07;ciaa1104, https://doi.org/10.1093/cid/ciaa1104. PMID: 31472402.
Heterogeneity in the cytokine profile of tuberculosis-diabetes co-morbidity Kumar NP, Moideen K, Nancy A, Viswanathan V, Shruthi BS, Sivakumar S, Natarajan M, Kornfeld H, Babu S. Cytokine 2020 Jan;125:154824. PMID: 31472402.
Impact of diabetes and low body mass index on tuberculosis treatment outcomes Kornfeld H, Sahukar BS, Procter-Gray E, Kumar NP, West K, Kane K, Natarajan M, Li W, Babu S, Viswanathan V. Clin Infect Dis. 2020 Jan 19. pii: ciaa054. doi: 10.1093/cid/ciaa054. [Epub ahead of print]. PMID: 31955202.
Clinical features associated with linezolid resistance among multidrug resistant tuberculosis patients at a tertiary care hospital in Mumbai, India Tornheim JA, Intini E, Gupta A, Udwadia ZFJ Clin Tuberc Other Mycobact Dis. 2020 Jul 24;20:100175. doi: 10.1016/j.jctube.2020.100175. eCollection 2020 Aug. PMID: 32775702; PMCID: PMC7398971.
COVID-19 -Tuberculosis interactions: When dark forces collide Udwadia ZF, Vora A, Tripathi AR, Malu KN, Lange C, Saru Raju R. Indian J Tuberc. 2020 Dec;67(4S):S155-S162. doi: 10.1016/j.ijtb.2020.07.003. Epub 2020 Jul 15. PMID: 33308662; PMCID: PMC7362784.
Whole genome enrichment approach for rapid detection of Mycobacterium tuberculosis and drug resistance-associated mutations from direct sputum sequencing Soundararajan L , Kambli P , Priyadarshini S, Let B , Murugan S, Iravatham C, Tornheim JA ,Rodrigues C, Gupta R , Ramprasad VL. Tuberculosis (Edinb). 2020 Mar;121:101915. doi: 10.1016/j.tube.2020.101915. Epub 2020 Feb 20. PMID: 32279871.
Toll-like receptor 2 polymorphisms and their effect on the immune response to ESAT-6, Pam3CSK4 TLR2 agonist in pulmonary tuberculosis patients and household contacts Mandala JP, Ahmad S, Pullagurla A, Thada S, Joshi L, Ansari MSS, Valluri VL, Gaddam SL. Cytokine. 2020 Feb;126:154897. doi: 10.1016/j.cyto.2019.154897. Epub 2019 Oct 31. PMID: 31678868.
Year 2019
IL-22 produced by type 3 innate lymphoid cells (ILC3s) reduces the mortality of type 2 diabetes mellitus (T2DM) mice infected with Mycobacterium tuberculosis Tripathi D, Radhakrishnan RK, Sivangala TR, Paidipally P, Devalraju KP, Neela VSK, McAllister MK, Samten B, Valluri VL, Vankayalapati R. PLoS Pathog. 2019 Dec 6;15(12):e1008140. PMID: 31809521.
Down regulation of RANTES in pleural site is associated with inhibition of antigen specific response in tuberculosis Pydi SS, Ghousunnissa S, Devalraju KP, Ramaseri SS, Gaddam R, Auzumeedi SK, Vankayalapati R, Valluri VL. Tuberculosis (Edinb). 2019 May;116S:S123-S130. PMID: 31103419.
Transcriptomic profiles of confirmed pediatric tuberculosis patients and exposed household contacts identifies tuberculosis disease, infection, and response to treatment among Indian patients Tornheim JA, Madugundu A, Paradkar M, Gupte N, Fukutani KF, Gupte AN, Kinikar A, Kulkarni V, Balasubramanian U, Sreenivasamurthy S, Raja R, Pradhan N, Shivakumar SVBY, Valvi C, Hanna LE, Andrade B, Padmapriyadarsini C, Mave V, Pandey A, Gupta A for the CTRIUMPh RePORT India Study Team. J Infect Dis. 2019 Dec 4. pii: jiz639. doi: 10.1093/infdis/jiz639. [Epub ahead of print]. PMID: 31796955.
Lipid mediators of inflammation and resolution in individuals with tuberculosis and tuberculosis-diabetes Shivakoti R, Dalli J, Kadam D, Gaikwad S, Barthwal M, Colas RA, Mazzacuva F, Lokhande R, Dharmshale S, Bharadwaj R, Kagal A, Pradhan N, Deshmukh S, Atre S, Sahasrabudhe T, Kakrani A, Kulkarni V, Raskar S, Suryavanshi N, Chon S, Gupte A, Gupta A, Gupte N, Arriaga MB, Fukutani KF, Andrade BB, Golub JE, Mave V. Prostaglandins Other Lipid Mediat. 2019 Nov 11;147:106398. doi: 10.1016/j.prostaglandins.2019.106398. [Epub ahead of print] PMID: 31726221.
Age-specific prevalence of TB infection among household contacts of pulmonary tuberculosis: Is it time for TB preventive therapy? Dolla CK , Padmapriyadarsini C, Thiruvengadam K, Lokhande R, Kinikar A, Paradkar M, Gupte A, Gaikwad S, Pradhan N, Kulkarni V, Shivakumar SVBY, Suryavanshi N, Gupte N, Pattabiraman S, Kagal A, Shrinivas BM, Murali L, Bharath TK, Pirthivi M, Kumaran P, Mave V, Gupta A. Trans R Soc Trop Med Hyg. 2019 Oct 11;113(10):632-640. doi: 10.1093/trstmh/trz049. PMID: 31225622; PMCID: PMC6792162.
Delays and barriers to early treatment initiation for childhood tuberculosis in India Valvi C, Chandanwale A, Khadse S, Kulkarni R, Kadam D, Kinikar A, Joshi S, Lokhande R, Garg P, Gupte N, Jain D, Suryavanshi N, Golub J, Shankar A, Gupta A, Dhumal G, DeLuca A, Bollinger RC. Int J Tuberc Lung Dis. 2019 Oct 1;23(10):1090-1099. doi: 10.5588/ijtld.18.0439. PMID: 31627774.
Smoking, alcohol use disorder and TB treatment outcomes: A dual co-morbidity burden that cannot be ignored Thomas B, Thiruvengadam K, Rani S, Ovung S, Sivakumar S, Shivakumar SVBY, Paradkar M, Gupte N, Suryavanshi N, Gupte AN, Kohli R, Pradhan N, Sivaramakrishnan GN, Gaikwad S, Kagal A, Dhanasekaran K, Deluca A, Golub JE, Mave V, Padmapriyadarsini C, Gupta A, CTRIUMPH-RePORT India Study. PLoS One. 2019 Jul 31;14(7):e0220507. doi: 10.1371/journal.pone.0220507. eCollection 2019. PMID: 31365583; PMCID: PMC6668833.
Infection free “resisters” among household contacts of adult pulmonary tuberculosis Mave V, Padmapriyadarsini C, Chavan A, Shivakumar SVBY, Danasekaran K, Paradkar M, Thiruvengadam K, Kinikar A, Murali L, Gaikwad S, Hannah LE, Kulkarni V, Pattabiraman S, Suryavanshi N, Thomas B, Kohli R, Sivaramakrishnan GN, Pradhan N, Banu B, Kagal A, Golub J, Gupte A, Gupte N, Swaminathan S, Gupta A. PLoS One. 2019;14(7):e0218034. Published 2019 Jul 18. doi:10.1371/journal.pone.0218034. PMID: 31318864; PMCID: PMC6638997.
Mobile phone access and comfort: Implications for HIV and tuberculosis care in India and South Africa Cox SN, Elf JL, Lokhande R, Ogale YP, DiAndreth L, Dupuis E, Milovanovic M, Mpongose N, Mave V, Suryavanshi N, Gupta A, Martinson N, Golub JE, Mathad JS. Int J Tuberc Lung Dis. 2019 Jul 1;23(7):865-872. doi: 10.5588/ijtld.18.0542. PMID: 31439120.
Assessment of lung function in successfully treated tuberculosis reveals high burden of ventilatory defects and COPD Gupte AN, Paradkar M, Selvaraju S, Thiruvengadam K, Shivakumar SVBY, Sekar K, Marinaik S, Momin A, Gaikwad A, Natrajan P, Prithivi M, Shivaramakrishnan G, Pradhan N, Kohli R, Raskar S, Jain D, Velu R, Karthavarayan B, Lokhande R, Suryavanshi N, Gupte N, Murali L, Salvi S, Checkley W, Golub J, Bollinger R, Mave V, Padmapriyadarsini C, Gupta A. PLoS One. 2019 PLoS One. 2019 May 23;14(5):e0217289. doi: 10.1371/journal.pone.0217289. eCollection 2019. PMID: 31120971; PMCID: PMC6532904.
Sub-therapeutic rifampicin concentration is associated with unfavourable tuberculosis treatment outcomes Ramachandran G, Padmapriyadarsini C, Gaikwad S, Kumar AKH, Kannan T, Gupte N, Paradkar M, Danasekaran K, Gomathi NS, Kagal A, Thomas B, Pradhan N, Kadam D, Hanna LE, Balasubramanian U, Kulkarni V, Murali L, Golub J, Gupte A, Shivakumar SVBY, Swaminathan S, Dooley KE, Gupta A, Mave V for the C-TRIUMPh team. Clin Infect Dis. 2019 May 10. pii: ciz380. doi: 10.1093/cid/ciz380. [Epub ahead of print]. PMID: 31075166.
Respiratory health status is associated with treatment outcomes in pulmonary tuberculosis Gupte AN, Selvaraju S, Paradkar M, Danasekaran K, Shivakumar SVB, Thiruvengadam K, Dolla C, Shivaramakrishnan G, Pradhan N, Kohli R, John S, Raskar S, Jain D, Momin A, Subramanian B, Gaikwad A, Lokhande R, Suryavanshi N, Gupte N, Salvi S, Murali L, Checkley W, Golub J, Bollinger R, Padmapriyadarsini C, Mave V, Gupta A. International Journal of Tuberculosis and Lung Disease April 2019 1; 23(4): 450-457. Int J Tuberc Lung Dis. 2019 Apr 1;23(4):450-457. doi: 10.5588/ijtld.18.0551. PMID: 31064624.
Diagnosis of TB Christopher DJ, Thangakunam B. Recent Advances in Pulmonary Medicine: Proceedings of 21st NAPCON 2019. Lung India. 2019 Nov:46-51.
Interaction of nutritional status and diabetes on active and latent tuberculosis: a cross-sectional analysis Kubiak R, Sarkar S, Horsburgh CR Jr, Roy G, Kratz M, Reshma, Knudsen S, Salgame P, Ellner JJ, Drain PK, Hochberg NS. BMC Infect Dis. 2019 Jul 16;19(1):627. doi: 10.1186/s12879-019-4244-4. PMID: 31311495; PMCID: PMC6636094.
Effect of malnutrition on radiographic findings and mycobacterial burden in pulmonary tuberculosis Hoyt K, Sarkar S, White LF, Joseph NM, Salgame P, Lakshminarayanan S, Muthaiah M, Kumar SV, Ellner, JJRoy G, Horsburgh CR Jr, Hochberg NS. PLoS ONE. 2019 Mar 27; 14(3). doi: 10.1371/journal.pone.0214011. PMID: 30917170; PMCID: PMC6436704.
Food for thought: The role of undernutrition and diabetes in India’s TB epidemic Sinha P, Hochberg NS. International Journal of Medicine and Public Health 2019;9(1):1-3.
Undernutrition and tuberculosis: Public health implications Sinha P, Davis J, Saag L, Wanke C, Salgame P, Mesick J, Horsburgh CR Jr, Hochberg NS. J Infect Dis. 2019 Apr 16;219(9):1356-1363. doi: 10.1093/infdis/jiy675. PMID: 30476125; PMCID: PMC6941617.
Crystal ball: The yesterday and tomorrow of tuberculosis Sinha P, Hochberg NS. Environ Microbiol Rep. 2019 Feb;11(1):41-44. doi: 10.1111/1758-2229.12726. Epub 2018 Dec 25. PMID: 30585431.
Systemic RAGE ligands are upregulated in tuberculosis individuals with diabetes co-morbidity and modulated by anti-tuberculosis treatment and metformin therapy Kumar NP, Moideen K, Nancy A, Viswanathan V, Shruthi BS, Sivakumar S, Hissar S, Kornfeld H, Babu S. BMC Infect Dis 2019 Dec 9;19(1):1039. PMID: 31818258; PMCID: PMC6902343.
Plasma chemokines are biomarkers of disease severity, higher bacterial burden and delayed sputum culture conversion in pulmonary tuberculosis Kumar NP, Moideen K, Nancy A, Viswanathan V, Shruthi BS, Sivakumar S, Natarajan M, Kornfeld H, Babu S. Sci Rep 2019 Dec 3;9(1):18217. PMID: 31796883; PMCID: PMC6890773.
Plasma eicosanoid levels in tuberculosis and tuberculosis-diabetes co-morbidity are associated with lung pathology and bacterial burden Kumar NP, Moideen K, Nancy A, Viswanathan V, Shruthi BS, Shanmugam S, Hissar S, Kornfeld H, Babu S. Front Cell Infect Microbiol 2019 Oct 1;9:335. PMID: 31632923; PMCID: PMC6779700.
Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity Kumar NP, Fukutani KF, Shruthi BS, Alves T, Silveira-Mattos PS, Rocha MS, West K, Natarajan M, Viswanathan V, Babu S, Andrade BB, Kornfeld H. eLife. 2019 Jul 4;8. pii: e46477. PMID: 31271354; PMCID: PMC6660216.
Elevated circulating levels of monocyte activation markers among tuberculosis patients with diabetes co-morbidity Kumar NP, Moideen K, Viswanathan V, Sivakumar S, Natarajan M, Kornfeld H, Babu S. Immunology. 2019 Mar;156(3):249-258. PMID: 30427060; PMCID: PMC6376263.
Delamanid central nervous system pharmacokinetics in tuberculous meningitis in rabbits and humans Tucker EW, Pieterse L, Zimmerman MD, Udwadia ZF, Peloquin CA, Gler MT, Ganatra S, Tornheim JA, Chawla P, Caoili JC, Ritchie B, Jain SK, Dartois V, Dooley KE. Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e00913-19. doi: 10.1128/AAC.00913-19. Print 2019 Oct. PMID: 31383662; PMCID: PMC6761520.
Management of drug-resistant tuberculosis Lange C, Dheda K, Chesov D, Mandalakas AM, Udwadia Z, Horsburgh CR Jr. Lancet. 2019 Sep14;394(10202):953-966. doi: 10.1016/S0140-6736(19)31882-3. PMID: 31526739.
A shorter regimen for rifampin-resistant tuberculosis Tornheim JA, Udwadia ZF, Gupta A. N Engl J Med. 2019 Sep 12;381(11):e22. doi: 10.1056/NEJMc1905782. PMID: 31509687.
Multi-centre study to establish interpretive criteria for clofazimine drug susceptibility testing Ismael N, Said HM, Rodrigues C ,Omar SV, Ajbani K, Sukhadia N, Kohl TA, Niemann S, Kranzer K, Diels M, Rigouts L, Rüsch-Gerdese S, Siddiqi S. Int J Tuberc Lung Dis. 2019 May 1;23(5):594-599. doi: 10.5588/ijtld.18.0417. PMID: 31097068.
Performance of bioMérieux Lowenstein-Jensen slopes in plastic tube packaging, compared to existing phenotypic methods, for efficient recovery of Mycobacterium tuberculosis (MTB) complex Nambiar R, Bereksi N, Gonzalez R, Anthony de Cozar, Loubet M, Shetty A, Alex van Belkum, Rodrigues C. J Med Microbiol. 2019 Mar;68(3):398-401. doi: 10.1099/jmm.0.000930. Epub 2019 Feb 6. PMID: 30724723.
Few eligible for the newly recommended short course MDR-TB regimen at a large Mumbai private clinic Udwadia ZF, Tornheim JA, Ganatra S, DeLuca A, Rodrigues CS, Gupta A.BMC Infectious Diseases 2019 Jan 28; 19:94, https://doi.org/10.1186/s12879-019-3726-8. PMID: 30691407; PMCID: PMC6350313.
Archives
2015, 2016, 2017, 2018
Year 2018
Building capacity for advances in tuberculosis research; proceedings of the third RePORT International meeting Van der Heijden YF, Abdullah F, Andrade BB, Andrews JR, Christopher DJ, Croda J, Ewing H, Haas DW, Hatherill M, Horsburgh CR Jr, Mave V, Nakaya HI, Rolla V, Srinivasan S, Sugiyono RI, Ugarte-Gil C, Hamilton C. Tuberculosis (Edinb). 2018;113: 153-162. PMID: 30514497; PMCID: PMC6349374.
Alcohol enhances type 1 interferon-αproduction and mortality of young mice infected with Mycobacterium tuberculosis Tripathi D, Welch E, Cheekatla SS, Radhakrishnan R, Venkatasubramanian S, Paidipally P, Van A, Samten B, Devalraju P, Neela V, Valluri V, Mason C, Nelson S and Vankayalapati R. PLoS Pathog. 2018 Aug 2;14(8):e1007174. doi: 10.1371/journal.ppat.1007174. eCollection 2018 Aug. PMID: 30071107; PMCID: PMC6072099.
IL-17 and IL-22 production in HIV+ individuals with latent and active tuberculosis Devalraju KP, Neela VSK, Ramaseri SS, Van A, Chaudhury A, Krovvidi SS, Vankayalapati R, Valluri VL. BMC Infect Dis. 2018 Jul 11;18(1):321. doi: 10.1186/s12879-018-3236-0. PMID: 29996789; PMCID: PMC6042451.
Defective MyD88 and IRAK4 but not TLR-2 expression in HIV+ individuals with latent tuberculosis infection Devalraju KP, Neela VSK, Gaddam R, Chaudhury A, Van A, Krovvidi SS, Vankaylapati R, Valluri VL. Cytokine. 2018 Oct;110:213-221. doi: 10.1016/j.cyto.2018.05.005. Epub 2018 May 17. PMID: 29778672; PMCID: PMC6103807.
Interleukin-21 regulates Natural Killer cell responses during mycobacterium tuberculosis infection Paidipally P, Tripathi D, Van A, Radhakrishnan RK, Dhiman R, Venkatasubramanian S, Devalraju KP, Tvinnereim AR, Valluri VL, Vankayalapati R. J Infect Dis. 2018 Mar 28;217(8):1323-1333. doi: 10.1093/infdis/jiy034. PMID: 29390153; PMCID: PMC6018723.
Association of TNF-α, IL-10 and IL-6 promoter polymorphisms in pulmonary tuberculosis patients and their household contacts of younger age group Joshi L, Chelluri LK, Valluri V, Gaddam S. Comp Immunol Microbiol Infect Dis. 2018 Feb;56:20-26. doi: 10.1016/j.cimid.2017.12.001. Epub 2017 Dec 26. PMID: 29406278.
Trends in HbA1c levels and implications for diabetes screening in tuberculosis cases undergoing treatment in India Gupte AN, Mave V, Meshram S, Lokhande R, Kadam D, Dharmshale S, Bharadwaj R, Kagal A, Pradhan N, Deshmukh S, Atre S, Sahasrabudhe T, Barthwal M, Meshram S, Kakrani A, Kulkarni V, Raskar S, Suryavanshi S, Shivakoti S, Chon S, Selvin E, Gupte N, Gupta A, Golub JE. Int J Tuberc Lung Dis. 2018 Jul 1;22(7):800-806. doi: 10.5588/ijtld.18.0026. PMID: 30041729; PMCID: PMC6198328.
Diabetes and prediabetes among household contacts of TB patients in India: Is it time to screen them all? Shivakumar SVBY, Padmapriyadarsini C, Kumar AMV, Paradkar M, Dhanasekaran K, Suryavanshi N, Thomas B, Kohli R, Thiruvengadam K, Kulkarni V, Hannah LE, Gomathy NS, Pradhan N, Dolla C, Gupte A, Ramachandran G, DeLuca A, Meshram S, Bharadwaj R, Bollinger RC, Golub J, Selvaraj K, Gupte N, Swaminathan S, Mave V, Gupta A for the CTRIUMPH- RePORT India Study Team. Int J Tuberc Lung Dis. 2018 Jun 1; 22(6): 686-694. Doi: 10.5588/ijtld.17.0598. PMID: 29862955.
Sources of household air pollution and their association with fine particulate matter in low-income urban homes in India Elf JL, Kinikar A, Khadse S, Mave V, Suryavanshi N, Gupte N, Kulkarni V, Patekar P, Raichur P, Breysse P, Gupta A, Golub JE. J Expo Sci Environ Epidemiol. 2018 Jun;28(4):400-410. Doi: 10.1038/s41370-018-0024-2. Epub 2018 May 23. PMID: 29789668; PMCID: PMC6013356.
Effect of diabetes mellitus on the pharmacokinetics and pharmacodynamics of tuberculosis treatment Alfarisi O, Mave V, Gaikwad S, Sahasrabudhe T, Ramachandran G, Kumar H, Gupte N, Kulkarni V, Deshmukh S, Atre S, Raskar S, Lokhande R, Barthwal M, Kakrani A, Chon S, Gupta A, Golub JE, Dooley KE. Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01383-18. doi: 10.1128/AAC.01383-18. Print 2018 Nov. PMID: 30126955; PMCID: PMC6201087.
Barriers to screening and isoniazid preventive treatment for child contacts tuberculosis patients Belgaumkar V, Chandanwale A, Valvi C, Pardeshi G, Lokhande R, Kadam D, Joshi S, Gupta N, Jain D, Dhumal G, Deluca A, Golub J, Shankar A, Gupta A, Kinikar A, Bollinger RC. Int J Tuberc Lung Dis. 2018 Oct 1;22(10):1179-1187. doi: 10.5588/ijtld.17.0848. PMID: 30236186.
The association of household fine particulate matter and kerosene with tuberculosis in women and children in Pune, India Elf JL, Kinikar A, Khadse S, Mave V, Suryavanshi N, Gupte N, Kulkarni V, Patekar S, Raichur P, Paradkar M, Kulkarni V, Pradhan N, Breysse PN, Gupta A, Golub JE. Occup Environ Med. 2018 Sep 7. pii: oemed-2018-105122. doi: 10.1136/oemed-2018-105122. [Epub ahead of print]. PMID: 30194271.
Tuberculin skin test and QuantiFERON-Gold In tube assay for diagnosis of latent TB infection among household contacts of pulmonary TB patients in a high TB burden setting Padmapriyadarsini C, Mave V, Thiruvengadam K, Gupte N, Shivakumar SVBY, Hanna LE, Kulkarni V, Kadam D, Dhanasekaran K, Paradkar M, Thomas B, Kohli R, Dolla C, Bharadwaj R, Sivaramakrishnan GN, Pradhan N, Gupte A, Murali L, Valvi C, Swaminathan S, Gupta A; CTRIUMPH Study Team. PLoS One. 2018 Aug 1;13(8):e0199360. doi: 10.1371/journal.pone.0199360. eCollection 2018. PMID: 30067752; PMCID: PMC6070176.
Addressing knowledge gaps and prevention for tuberculosis-infected Indian adults: A vital part of elimination Deluca A, Dhumal G, Paradkar M, Suryavanshi N, Mave V, Kohli R, Shivakumar SVBY, Hulyolkar V, Gaikwad A, Nangude A, Pardeshi G, Kadam D, Gupta A. Published in BMC Infectious Diseases, May 2018. BMC Infect Dis. 2018 May 2;18(1):202. doi: 10.1186/s12879-018-3116-7. PMID: 29720095; PMCID: PMC5932769.
Second hand smoke exposure and validity of self-report in low-income women and children in India Elf J, Kinikar A, Khadse S, Mave V, Gupte N, Kulkarni V, Patekar V, Raichur P, Cohen J, Breysse PN, Gupta A, Golub JE. Pediatrics. 2018 Jan; 141 (Suppl 1): S118-S129. doi: 10.1542/peds.2017-1026O. PMID: 29292312; PMCID: PMC5745676.
Thoracoscopic pleural biopsy improves yield of Xpert MTB/RIF for diagnosis of pleural tuberculosis Christopher DJ, Dinakaran S, Gupta R, James P, Isaac B, Thangakunam B. Respirology. 2018 Jul;23(7):714-717. Epub 2018 Feb 27. doi: 10.1111/resp.13275. PMID: 29486527.
Low BMI and latent tuberculosis infection: A systematic review and meta-analysis Saag LA, LaValley MP, Hochberg NS, Cegielski P, Pleskunas JA, Linas B, Horsburgh CR. Int J Tuberc Lung Dis. 2018 Apr 1;22(4):358-365. doi: 10.5588/ijtld.17.0558. PMID: 29562981.
Existing blood transcriptional classifiers accurately discriminate active tuberculosis from latent infection in individuals from South India Leong, S, Yue Zhao, Joseph NM, Hochberg NS, Sarkar S, Pleskunas J, Hom D, Lakshminarayanan S, Horsburgh Jr, CR, Roy G, Ellner JJ, Johnson WE, Salgame, P. Tuberculosis (Edinb). 2018 Mar;109:41-51. doi: 10.1016/j.tube.2018.01.002. Epub 2018 Jan 31. PMID: 29559120.
Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment Kumar NP, Moideen K, Viswanathan V, Sivakumar S, Menon PA, Kornfeld H, Babu S. BMC Infect Dis. 2018 Jul 25;18(1):345. PMID: 30045688; PMCID: PMC6060542.
Utility of pyrosequencing for rapid detection of tubercular meningitis (TBM) and associated susceptibility directly from CSF specimens Ajbani K, Kazi M, Naik S, Soman R, Shetty A, Rodrigues C. Tuberculosis (Edinb). 2018 Jul;111:54-56. doi: 10.1016/j.tube.2018.05.009. Epub 2018 May 19. PMID: 30029915.
Evaluation of pyrosequencing for extensive drug resistance-defining anti-tuberculosis drugs for use in public healthcare Nambiar R, Shah D, Ajbani K, Kazi M, Sadani M, Shetty A, Keskar P, Kamble S, van Belkum A, Rodrigues C. Tuberculosis (Edinb). 2018 May;110:86-90. doi: 10.1016/j.tube.2018.03.006. Epub 2018 Mar 26. PMID: 29779779.
Pyrosequencing to resolve discrepant Xpert MTB/RIF and Mycobacterial Growth Indicator Tube 960 Ajbani K, Kazi M, Tornheim J, Naik S, Soman R, Shetty A, Rodrigues C. Lung India. 2018 Mar-Apr;35(2):168-170. doi: 10.4103/lungindia.lungindia_71_17. PMID: 29487256; PMCID: PMC5846270.
Year 2017
IL-21-dependent expansion of memory-like NK cells enhances protective immune responses against Mycobacterium tuberculosis
Venkatasubramanian S, Cheekatla S, Paidipally P, Tripathi D, Welch E, Tvinnereim AR, Nurieva R, Vankayalapati R. Mucosal Immunol. 2017 Jul;10(4):1031-1042. doi: 10.1038/mi.2016.105. Epub 2016 Dec 7. PMID: 27924822; PMCID: PMC5462891.
IL-6 and IL-18 cytokine gene variants of pulmonary tuberculosis patients with co-morbid diabetes mellitus and their household contacts in Hyderabad
Ponnana M, Sivangala R, Joshi L, Valluri V, Gaddam S. Gene. 2017 Sep 5;627:298-306. doi: 10.1016/j.gene.2017.06.046. Epub 2017 Jun 23. PMID: 28652186.
Isoniazid concentrations in hair and plasma area-under-the-curve exposure among children with tuberculosis
Mave V, Kinikar A, Kagal A, Nimkar S, Koli H, Khwaja S, Bharadwaj R, Gerona R, Wen A, Ramachandran G, Kumar H, Bacchetti P, Dooley KE, Gupte N, Gupta A, Gandhi M. PLoS One. 2017 Dec 7;12(12):e0189101. doi: 10.1371/journal.pone.0189101. PMID: 29216273; PMCID: PMC5720757.
Prevalence of dysglycemia and clinical presentation of pulmonary tuberculosis in Western India
Mave V, Meshram S, Lokhande R, Kadam D, Dharmshale S, Bharadwaj R, Kagal A, Pradhan N, Deshmukh S, Atre S, Sahasrabudhe T, Barhwal M, Meshram S, Kakrani A, Kulkarni V, Raskar S, Suryavanshi N, Shivakoti R, Chon S, Selvin E, Gupte A, Gupta A, Gupte N, Golub J. Int J Tuberc Lung Dis. 2017 Dec 1;21(12):1280-1287. doi: 10.5588/ijtld.17.0474. PMID: 29297449; PMCID: PMC6203962.
Comorbidities in pulmonary tuberculosis cases in Puducherry and Tamil Nadu, India: Opportunities for intervention
Hochberg NS, Sarkar S, Horsburgh, Jr, CR, Knudsen S, Pleskunas J, Sahu S, Kubiak RW, Govindarajan S, Salgame P, Lakshminarayanan S, Sivaprakasam A, White LF, Joseph NM, Ellner JJ, Roy G. PLoS One. 2017 Aug 23;12(8):e0183195. doi: 10.1371/journal.pone.0183195. eCollection 2017. PMID: 28832615; PMCID: PMC5568341.
Predictors of delayed care seeking for tuberculosis in Southern India: An observational study
Van Ness SE, Chandra A, Sarkar S, Pleskunas J, Ellner JJ, Roy G, Lakshminarayanan S, Sahu S, Horsburgh Jr CR, Jenkins HE, Hochberg NS. BMC Infect Dis. 2017 Aug 15;17(1):567. doi: 10.1186/s12879-017-2629-9. PMID: 28806911; PMCID: PMC5557420.
Systems immunology of diabetes tuberculosis comorbidity reveals signatures of disease complications
Prada-Medina CA, Fukutani KF, Kumar NP, GilSantana L, Babu S, Lichtenstein F, West K, Sivakumar S, Menon PA, Viswanathan V, Andrade BB, Nakaya H, Kornfeld H. Sci Rep. 2017 May 17;7(1):1999. PMID: 28515464; PMCID: PMC5435727.
Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 2: Underlying biological mechanisms
Ronacher K, van Crevel R, Critchley J, Bremer A, Schlesinger LS, Kapur A, Basaraba R, Kornfeld H, Restrepo BI. Chest. 2017 Jul;152(1):174-180. PMID: 28434937; PMCID: PMC5577357.
Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 1: Epidemiology and clinical management
Critchley JA, Restrepo BI, Ronacher K, Kapur A, Bremer AA, Schlesinger LS, Basaraba R, Kornfeld H, van Crevel R. Chest. 2017 Jul;152(1):165-173. PMID: 28434936; PMCID: PMC5989639.
Tuberculosis-diabetes co-morbidity is characterized by heightened systemic levels of circulating angiogenic factors
Kumar NP, Moideen K, Sivakumar S, Menon PA, Viswanathan V, Kornfeld H, Babu S. J Infect. 2017 Jan;74(1):10-21. PMID: 27717783; PMCID: PMC5164955.
Heightened circulating levels of antimicrobial peptides in tuberculosis-diabetes co-morbidity and reversal upon treatment
Kumar NP, Moideen K, Viswanathan V, Sivakumar S, Menon PA, Kornfeld H, Babu S. PLoS One. 2017 Sep 14;12(9):e0184753. doi: 10.1371/journal.pone.0184753. eCollection 2017. PMID: 28910369; PMCID: PMC5599016.
Year 2016
NK-CD11c+ cell crosstalk in diabetes enhances IL-6-mediated inflammation during Mycobacterium tuberculosis infection Cheekatla SS, Tripathi D, Venkatasubramanian S, Nathella PK, Paidipally P, Ishibashi M, Welch E, Tvinnereim AR, Ikebe M, Valluri VL, Babu S, Kornfeld H, Vankayalapati R. PLoS Pathog. 2016 Oct 26;12(10):e1005972. doi: 10.1371/journal.ppat.1005972. eCollection 2016. PMID: 27783671; PMCID: PMC5082658.
Polymorphisms of IFN-γ (+874A/T) and IL-12 (+1188A/C) in tuberculosis patients and their household contacts in Hyderabad, India Thada S, Ponnana M, Sivangala R, Joshi L, Alasandagutti M, Ansari MS, Schumann RR, Valluri V, Gaddam S. Hum Immunol. 2016 Jul;77(7):559-65. doi: 10.1016/j.humimm.2016.04.016. Epub 2016 Apr 22. PMID: 27108964.
Cytokine production and mRNA expression in pulmonary tuberculosis patients and their household contacts of younger age group Joshi L, Ponnana M, Sivangala R, Chelluri LK, Nallari P, Valluri VL, Gaddam S. J Immunol Methods. 2016 May;432:65-71. doi: 10.1016/j.jim.2016.02.012. Epub 2016 Feb 12. PMID: 26876300.
Isoniazid hair concentrations in children with tuberculosis: A proof of concept study Mave V, Chandanwale A, Kinikar A, Khadse S, Kagal A, Gupte N, Suryavanshi N, Nimkar S, Koli H, Khwaja S, Bharadwaj R, Joshi S, Horng H, Benet LZ, Ramachandran G, Dooley KE, Gupta A, Gandhi M. Int J Tuberc Lung Dis. 2016 Jun; 20(6): 844–847. doi: 10.5588/ijtld.15.0882. PMID: 27155191; PMCID: PMC4889729.
Cohort for Tuberculosis Research by the Indo-U.S. Medical Partnership (CTRIUMPH): Protocol for a multicentric prospective observational study Gupte A, Padmapriyadarsini C, Mave V, Kadam D, Suryavanshi N, Shivakumar SVBY, Kohli R, Gupte N, Thiruvengadam K, Kagal A, Meshram S, Bharadwaj R, Khadse S, Ramachandran G, Hanna LE, Pradhan N, Gomathy NS, DeLuca A, Gupta A, Swaminathan S; CTRIUMPH Study Team. BMJ Open 2016 Feb 25;6(2):e010542. PMID: 26916698; PMCID: PMC4769396.
Modulation of dendritic cell and monocyte subsets in tuberculosis-diabetes co-morbidity upon standard tuberculosis treatment Kumar NP, Moideen K, Sivakumar S, Menon PA, Viswanathan V, Kornfeld H, Babu S. Tuberculosis (Edinb). 2016 Dec; 101:191-200. PMID: 27865391; PMCID: PMC5127284.
Effect of standard tuberculosis treatment on naive, memory and regulatory T-cell homeostasis in tuberculosis-diabetes co-morbidity Kumar NP, Moideen K, Viswanathan V, Kornfeld H, Babu S. Immunology. 2016 Sep;149(1):87-97. PMID: 27289086; PMCID: PMC4981606.
Glucose metabolism disorder is associated with pulmonary tuberculosis in individuals with respiratory symptoms from Brazil Almeida-Junior JL, Gil-Santana L, Oliveira CA, Castro S, Cafezeiro AS, Daltro C, Netto EM, Kornfeld H, Andrade BB. PLoS One. 2016 Apr 14;11(4):e0153590. PMID: 27078026; PMCID: PMC4831681.
High prevalence and heterogeneity of diabetes in patients with TB in South India: A report from the Effects of Diabetes on Tuberculosis Severity (EDOTS) Study Kornfeld H, West K, Kane K, Kumpatla S, Zacharias RR, Martinez-Balzano C, Li W, Viswanathan V. Chest. 2016 Jun;149(6):1501-8. PMID: 26973015; PMCID: PMC4944775.
Year 2015
RePORT International: Advancing tuberculosis biomarker research through global collaboration
Hamilton CD, Swaminathan S, Christopher DJ, Ellner J, Gupta A, Sterling TR, Rolla V, Srinivasan S, Karyana M, Siddiqui S, Stoszek SK, Kim P. Clinical Infectious Diseases (CID). 2015 October 15; 61(Suppl 3): S155–S159. PMID: 26409277; PMCID: PMC4583572.
